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To determine whether the observed defect in lipid scrambling resulted from disruptions in upstream signaling events, we next analyzed the early molecular pathways involved in PMA-induced NET formation

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Although ultracentrifugation has been acccepted as the gold standard for exosome isolation, several issues remain to be addressed, such as expensive equipment, long processing time (4 6 hours), limited recovery rate, and purity problems caused by co-precipitation of other extracellular vesicles and protein complexes (127)

[3] [8] [1] [6] [154] Some say chemical industry interest groups have funded these efforts, and indeed some of the most vocal writers with anti-MCS stances have also been industry-paid expert witnesses in legal cases involving alleged chemical injuries